The Lock Atoms tool is used to block additional substitution at an atom site. You can lock any number of atom sites within a structure. Terminal shortcuts (e.g., Me) are locked by definition.
Click the Lock Atoms icon.
Click the atom that you want to lock. A box appears around the atom indicating that it is blocked from substitution.
Click the Lock Atoms icon.
Click the locked atom. The box is removed indicating that substitution is allowed at the atom site.
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Drawing and Editing Structures