Structure Search Options in STNext

Structure Search Type

Retrieval

Use Variables?

EXA (exact)

Stereoisomers, charged, and isotopically labeled structures

No

FAM (family)

Stereoisomers, charged, and isotopically labeled structures
+ salts, mixtures

No

CSS (closed substructure search)

Stereoisomers, charged, and isotopically labeled structures, salts, mixtures
+ substances with no substitutions at open nodes unless the query is specified for substitution

Yes

SSS (substructure search)

Stereoisomers, charged, and isotopically labeled structures, salts, mixtures, substances with no substitutions at open nodes unless the query is specified for substitution
+ analogs and derivatives of a core structure

Use SSS search to find substances that match the query with any and all substitution

allowed. You may block substitution with, for example, hydrogen counts, non-hydrogen

attachments, and shortcut symbols. Additional components may also be retrieved. This

is the broadest and most powerful of all the search types. It retrieves all substances

in the database containing at least the atoms and bonds described in the structure

query; but, the query may be embedded in any larger substance. The SSS search retrieves

all the EXACT, FAMILY, and CSS answers, as well as any substances that have substitution.

The SSS search is the default search type.

Yes